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Get lots of sunshine for immune system support

Vitamin D is being shown to mitigate the severity of Covid-19 infection

Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths William B. Grant, Henry Lahore, Sharon L. McDonnell, Carole A. Baggerly, Christine B. French, Jennifer L. Aliano, and Harjit P. Bhattoa Nutrients 2020, 12(4), 988

This recently published paper details the current research in support of higher vitamin D serum levels and decreased incidence of viral-induced respiratory diseases.

Through several mechanisms, vitamin D can reduce risk of infections.Those mechanisms include inducing cathelicidins and defensins that can lower viral replication rates and reducing concentrations of pro-inflammatory cytokines that produce the inflammation that injures the lining of the lungs, leading to pneumonia, as well as increasing concentrations of anti-inflammatory cytokines.

First data to be published on COVID-19 severity and vitamin D levels: Vitamin D Supplementation Could Possibly Improve Clinical Outcomes of Patients Infected with Coronavirus-2019 (Covid-2019)

In this preprint letter (not yet peer reviewed), data is presented from 212 COVID-19 patients who were hospitalised in three separate hospitals in Southern Asia comparing the severity of symptoms to vitamin D serum levels. Of the 212 cases, the average vitamin D level was 24 ng/ml (59 nmol/L)

  • 49 (23%) cases were categorized as mild, with an average vitamin D level of 31 ng/ml (78 nmol/L)

  • 59 (28%) were categorized as ordinary, with an average vitamin D level of 27 ng/ml (68 nmol/L)

  • 56 (26%) were categorized as severe, with an average vitamin D level of 21 ng/ml (53 nmol/L)

  • 48 (23%) were critical, with an average vitamin D level of 17 ng/ml (43 nmol/L)

  • 86% of all cases among patients with normal vitamin D levels were mild, while 73% of cases among patients with vitamin D deficiency were severe or critical

  • For each standard deviation increase in vitamin D level, the odds of having a mild case compared to a severe case were 7.94 times more, and the odds of having a mild case compared to a critical case were 19.61 times more

All outcomes were statistically significant.

The odds of having a mild clinical outcome increase when serum (OH)D level increases. Alternatively, the odds of having a critical outcome increase when serum (OH)D level decreases. This means that serum(OH)D level in the body could account for the clinical outcomes of the patients infected with Covid-2019. An increase in serum (OH)D level in the body could either improve clinical outcomes or mitigate worst (severe to critical) outcomes. On the other hand, a decrease in serum (OH)D level in the body could worsen clinical outcomes of Covid-2019 patients.

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